WebNov 15, 2013 · It is then converted into the compatible solutes ectoine and 5-hydroxyectoine, respectively, by the L-2,4-diaminobutyrate transaminase (EctB; EC: 2.6.1.76) to form L-2,4-diaminobutyrate, a metabolite that is then acetylated by the 2,4-diaminobutyrate acetyltransferase (EctA; EC: 2.3.1.178) to produce N-γ-acetyl-2,4 … WebAug 14, 2024 · The second step in ectoine biosynthesis is catalyzed by l-2,4-diaminobutyrate acetyltransferase (EctA; EC 2.3.1.178), which transfers the acetyl group from acetyl-CoA to EctB-formed l-2,4-diaminobutyrate (DAB), yielding N -γ-acetyl-l-2,4-diaminobutyrate ( N -γ-ADABA), the substrate of ectoine
diaminobutyrate acetyltransferase - Creative Biogene
WebTherefore, we conclude that the EctA l-2,4-diaminobutyrate acetyltransferase transfers the acetyl group from the co-substrate to the substrate in a highly position-specific manner. Figure 2 ( Pl )EctA-dependent N -γ-acetyl- l -2,4-diaminobutyrate production and kinetic parameters of the ( Pl )EctA enzyme. Webdiaminobutyrate acetyltransferase. Product Information. Cat # MEVP-1785 . Similar. acetyltransferase. Enzyme Commission Number. EC 2.3.1.178 . Product Overview. High-quality enzyme products. Well-established quality management system. Reaction. acetyl-CoA + L-2,4-diaminobutanoate = CoA + (2S)-4-acetamido-2-aminobutanoate . involved vs committed
ExplorEnz: EC 2.3.1.178 - enzyme-database.org
WebReshetnikov, A.S.; Mustakhimov, II; Khmelenina, V.N.; Trotsenko, Y.A.: Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the … WebMay 14, 2024 · Ectoine is a high-value stabilizer and protective agent with various applications in enzyme industry, cosmetics, and biomedicine. In this study, rational engineering strategies have been implemented in Escherichia coli to efficiently produce ectoine. First, the synthetic pathway of ectoine was constructed in E. coli MG1655 by … WebEC: 2.3.1.178 : Accepted name: diaminobutyrate acetyltransferase: Reaction: acetyl-CoA + L-2,4-diaminobutanoate = CoA + (2S)-4-acetamido-2-aminobutanoate For diagram of ectoine biosynthesis, click here Other name(s): L-2,4-diaminobutyrate acetyltransferase; L-2,4-diaminobutanoate acetyltransferase; EctA; diaminobutyric acid … involved uninvolved free light chain