Fbxo22 possesses both
WebApr 6, 2024 · Based on the finding that nuclear PTEN is more unstable than cytoplasmic PTEN, here we identify that F-box only protein 22 (FBXO22) induces ubiquitylation of nuclear but not cytoplasmic PTEN at lysine 221, which is responsible for the degradation of nuclear PTEN. FBXO22 plays a tumor-promoting role by ubiquitylating and degrading …
Fbxo22 possesses both
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WebJul 29, 2024 · F-box and leucine-rich repeat protein 7 (FBXL7), an F-box protein responsible for substrate recognition by the SKP1-Cullin-1-F-box (SCF) ubiquitin ligases, plays an emerging role in the regulation... WebSep 16, 2024 · The protein level of Fbxo22 was elevated in MDA-MB-231 and Hs578T cells treated with Flag-Fbxo22, while the protein level of KDM5A was diminished (Fig. 2C). …
WebJan 24, 2024 · F-box only protein 22 (FBXO22), a substrate receptor of the SKP1-Cullin 1-F-box protein (SCF) E3 ubiquitin ligase that targets key regulators of cellular activities for ubiquitylation and degradation, plays important roles in the progression of human cancer. However, little is known about the role of FBXO22 in renal cell carcinoma (RCC). WebOct 1, 2016 · FBXO22 Possesses Both Protumorigenic and Antimetastatic Roles in Breast Cancer Progression. 19: 26087183: 2015: F-box protein FBXO22 mediates …
WebThe tissue microarray (TMA)-based immunohistochemistry (IHC) on 106 CRC cases showed that ESCO2 localized in both nuclear and cytoplasm. Positive immunoreactivity was depicted in 81.1% (86/106) of cancerous ... Xie HY, Qian JX, et al. FBXO22 possesses both protumorigenic and antimetastatic roles in breast cancer progression. Cancer Res. … WebJun 26, 2024 · Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. [email protected] [email protected]. Cancer Research , 26 Jun 2024, 78 (18): 5274-5286. DOI: 10.1158/0008-5472.can-17-3647 PMID: 29945959.
WebJul 2, 2024 · Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis. - Abstract - Europe PMC Europe PMC is an archive of life sciences journal literature. Europe PMC
WebJun 19, 2024 · Sun, R. et al. FBXO22 possesses both protumorigenic and antimetastatic roles in breast cancer progression. Cancer Res. 78 , 5274–5286 (2024). Article CAS … phim hen ho cong so tap 7WebNov 22, 2024 · The tissue microarray (TMA)-based immunohistochemistry (IHC) on 106 CRC cases showed that ESCO2 localized in both nuclear and cytoplasm. Positive immunoreactivity was depicted in 81.1% (86/106) of cancerous ... Xie HY, Qian JX, et al. FBXO22 possesses both protumorigenic and antimetastatic roles in breast cancer … t slim infusion sets soreWebJun 26, 2024 · FBXO22 Possesses Both Protumorigenic and Antimetastatic Roles in Breast Cancer Progression. @article{Sun2024FBXO22PB, title={FBXO22 Possesses … t slim infusionWebOct 1, 2002 · FBXO22. Synonyms. FBX22. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo. … t slim dexcom closed loopWebJun 11, 2024 · In human breast cancer cells, FBXO22 knockdown (KD) increased cell invasiveness, which was driven by elevated levels of HDM2. Moreover, mouse 4T1 … tslim infusion set change youtubeWebJul 27, 2024 · FBXO22 is also regulated by several regulatory factors such as p53, miR-155, SNHG14, and circ_0006282. ... Sun, R. et al. FBXO22 possesses both protumorigenic … tslim infusion set typesWebJun 14, 2024 · Of these, FBXO22, an F-box receptor subunit of SCF E3 ligase, has recently been proposed to play a critical role in multiple aspects related to cancer development and therapy response. Firstly, FBXO22 is a key regulator of senescence induction through ubiquitylation of p53 for degradation. FBXO22 also acts as a molecular switch for the ... phim hero class