NettetLINE 1 ORF1p Rabbit pAb. Gene Name ... Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. ... Primary Antibody. Host Rabbit. Reactivity Human. Application WB,IHC-P. … Nettet31. des. 2024 · Long interspersed element-1 (LINE-1, L1) is the major driver of mobile DNA activity in modern humans. When expressed, LINE-1 loci produce bicistronic …
Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p …
NettetAnti-LINE-1 ORF1p Antibody, clone 4H1 Detect LINE-1 retrotransposable element ORF1 protein using this mouse monoclonal Anti-LINE-1 ORF1p Anibody, clone 4H1, Cat. No. … Nettet1. jun. 2024 · The LINE1-ORF1p antibody prepared had a titer of >1:16 000 and could specifically recognize LINE1-ORF1p in cells and tumor tissue. WT_CLS1 cells transfected with pEGFP-N1-LINE1-ORF1 had significant increases in the mRNA and protein expression of LINE1-ORF1 and significantly enhanced cell proliferation ability and … cci france thailande
Anti-LINE-1 ORF1p Antibody, clone 4H1 MABC1152
Nettet31. des. 2024 · When expressed, LINE-1 loci produce bicistronic transcripts encoding two proteins essential for retrotransposition, ORF1p and ORF2p. Many types of human … NettetAnti-mouse LINE-1 ORF1p rabbit polyclonal antibodies. This fantastic reagent was developed and characterized by Sandy Martin in 1991. As the piRNA field took off in 2006, this polyclonal antibody has become very popular following our first description of Maelstrom knockout male mice. Nettet3. jan. 2024 · ORF1p, a nucleic acid chaperone that binds LINE-1 mRNA, was predominantly expressed in the cytoplasm, with minor localization in the nucleus. ORF2p, containing endonuclease and reverse transcriptase domains, exhibited punctate foci in the nucleus and also displayed co-localization with PCNA and γH2AX. ccif strategic initiatives