WebFeb 4, 2024 · Phosphorogenic Iridium (III) bis -Tetrazine Complexes for Bioorthogonal Peptide Stapling, Bioimaging, Photocytotoxic Applications, and the Construction of Nanosized Hydrogels Alex Man-Hei Yip, Calvin Kin-Ho Lai, Dr. Ken Shek-Man Yiu, Prof. Kenneth Kam-Wing Lo First published: 04 February 2024 … WebJan 21, 2015 · New phosphorogenic bioorthogonal probes derived from mononuclear and binuclear rhenium(I) polypyridine complexes containing a 1,2,4,5-tetrazine moiety were designed; these complexes displayed substantial dienophile-induced emission enhancement, and accelerated reaction kinetics and could target a protein conjugate in …
Phosphorogenic sensors for biothiols derived from …
WebBioorthogonal Phosphorogenic Rhenium (I) Polypyridine Sydnone Complexes for Specific Lysosome Labeling Bioorthogonal Phosphorogenic Rhenium (I) Polypyridine Sydnone Complexes for Specific Lysosome Labeling Chempluschem. 2024 Jul;85 (7):1368. doi: 10.1002/cplu.202400346. Epub 2024 Jun 3. Authors WebJun 7, 2016 · We report a new class of ruthenium(II) polypyridine complexes functionalized with a nitrone group as phosphorogenic bioorthogonal probes. These complexes were … i phytoral 100
Phosphorogenic Iridium (III) - Wiley Online Library
WebMar 5, 2024 · Herein, we report the synthesis, characterization, and photophysical properties of rhenium(I) polypyridine complexes containing a sydnone moiety as bioorthogonal phosphorogenic probes. Their reactions with strained alkyne derivatives and the associated photophysical changes were examined. WebOct 1, 2016 · The possible phosphorogenic responses of the tetrazine complexes towards BCN-BSA were also investigated. Impressively, the emission enhancement factors of the complexes upon the bioconjugation reaction went up to 140.8–1133.7 ( Table 3 and Fig. 5 ). WebThe development of phosphorogenic bioorthogonal probes requires the modification of transition metal complexes with an emission quencher that also serves as a bioorthogonal handle. The most commonly studied examples include: 1) 1,2,4,5-tetrazines which undergo inverse electron-demand Diels–Alder (IEDDA) reactions with dienophiles and 2 ... i photo you